Ovasitol Frequently Asked Questions

Ovasitol is a unique supplement for any woman with PCOS that combines myo- and d-chiro-inositol in the body’s naturally occurring ratio of 40 to 1.  This ideal ratio has been shown to reduce insulin, regulate periods, restore hormone balance, and improve egg quality and ovulation. Many women who take Ovasitol report a significant reduction in carbohydrate cravings. Here are the answers to the most common questions about Ovasitol for PCOS.

Can I take Ovasitol with Metformin?  Does this replace Metformin or do I take it with?

Please ask your doctor or other healthcare provider about taking Ovasitol with Metformin, or taking Ovasitol instead of Metformin.  Because both inositol and Metformin have been shown to affect insulin levels and restore ovulation, they may have additive effects.  In one study comparing myo-inositol to Metformin, myo-inositol showed slightly better results for restoring ovulation and increasing pregnancy rates. You can take Ovasitol and Metformin at the same time. This article about taking the two together may be helpful.

Can I take Ovasitol and other supplements?

Yes, Ovasitol is compatible with all the supplements sold in the PCOS Nutrition Center Store


Can I take Ovasitol if breastfeeding?

Yes, Ovasitol can be taken while breastfeeding your baby. We still recommend talking with your doctor first.


Can I take Ovasitol if pregnant?

Yes, Ovasitol can be taken throughout pregnancy. Taking inositol during pregnancy may be beneficial.  Studies have shown that myo-inositol supplementation during pregnancy significantly reduces the risk of gestational diabetes.


Is it available in Canada?


Ships FREE!

Yes, Ovasitol is available for FREE shipping to Canada.  Order here


I live outside of the United States and Canada. How can I get this?

Sorry, We cannot ship outside of the U.S. and Canada.


How long does it take to receive my order?

Your initial order of Ovasitol should arrive within a week if shipped within the US. Orders to Canada may take 2-3 weeks. Theralogix, the makers of Ovasitol will send you tracking information once it ships.


Will this help me regulate my periods?

Yes, studies show that inositol helps regulate a woman’s menstrual cycle (period), and restore normal ovulation.


How should Ovasitol best be taken?

Ovasitol can be mixed into any hot or cold beverage with the exception of carbonated soft drinks and alcohol. It is best taken along with a meal in two divided doses.


Does Ovasitol have side effects?

Overall, Ovasitol is well tolerated. We recommend starting with one dose a day with a meal for the first week to minimize any risk for a side effect. Inositol, at the dose found in Ovasitol, is not expected to cause stomach upset.  However, if you do experience stomach upset, try taking Ovasitol with a meal.  For example, mix one packet of Ovasitol into liquid and drink with your breakfast, and mix one packet of Ovasitol into liquid and drink along with your dinner. It’s also great in a smoothie.



What does Ovasitol taste like?

Ovasitol is a tasteless powder. Since everyone is different and has different tastebuds, it could vary. Some say it tastes a little sweet.


Can Ovasitol help me lose weight?

According to the research, inositol may help with weight loss. Some studies have shown that women taking inositol have significant weight loss compared to women taking a placebo.  It is important to continue eating a healthful diet and being physically active while taking Ovasitol.


Is this something to take to help get pregnant or for PCOS in general?

Ovasitol can be taken by women who are trying to get pregnant and by those who are not trying.  Research shows that inositol helps to improve fertility chances by regulating menstruation (monthly period) and improving ovulation.  Inositol has also been shown to improve egg quality, which is important for women trying to get pregnant.

Why hasn’t my doctor heard of this?

Your doctor may or may not have heard about Ovasitol.  Ovasitol is a new inositol product combining myo- and d-chiro-inositol in the body’s naturally occurring ratio of 40 to 1.  This inositol combination has been shown to be more beneficial than either form of inositol alone.


What if I don’t have insulin resistance? Will Ovasitol help me?

Ovasitol has been shown to restore hormone balance and regulate periods. Many women who take it find it helps reduce cravings. Other uses of Ovasitol are to help with acne and mood.


I’m not trying to get pregnant. Can I still take Ovasitol?

For women who are not trying to get pregnant, or older women who are past menopause, inositol has also been shown to lower insulin, testosterone, triglyceride, and blood pressure levels, and increase HDL (“good”) cholesterol levels. Many women who take Ovasitol also see a reduction in cravings for carbohydrate foods and sweets.


Can I give Ovasitol to my teenage daughter?

Yes, Ovasitol has been shown to be safe in children as young as 8 years of age. For many, taking Ovasitol can regulate periods, reducing the need to take birth control medications.


What makes Ovasitol so much better than other forms of inositol?

Ovasitol is unique in that it combines myo- and d-chiro-inositol in the body’s naturally occurring ratio of 40 to 1.  This ideal ratio has been shown to work better than myo or d-chiro inositol alone. Too much d-chiro inositol has been shown to worsen egg quality. Ovaitol is pharmaceutical-grade and is the only inositol supplement to be independently tested by a non-profit third party to assure purity and accuracy.


Why do the Ovasitol packets cost more than the canister?

The extra cost is due to the materials for the packets and the process of packaging the individual packets. Many woman like the packets because they are easy to travel with or take on the go so you never miss a dose. Both contain a 3-month supply of Ovasitol.

Leave A Comment

Your email address will not be published. Required fields are marked *

Comments (218)
  • Lerhonda Adams

    October 17, 2018 at 9:22 am

    I just wanted to know is this supplement safe to take during pregnancy and if so for how long and if not should a person that becomes pregnant should they stop taking the supplement ?

  • Angela Grassi

    November 5, 2018 at 2:01 pm

    Every woman is different so I suggest you talk with your doctor if she/he wants you to continue. Ovasitol has been shown to lower the risk for gestational diabetes: http://www.pcosnutrition.com/inositols-decrease-gestational-diabetes-pcos-women/

  • Citlaly

    November 2, 2018 at 10:32 pm

    Can Ovasitol help you get pregnant?

  • Angela Grassi

    November 5, 2018 at 1:54 pm

    Yes, Ovasitol has been shown to improve egg quality and ovulation to help you get pregnant.

  • Deborah

    November 5, 2018 at 1:23 pm

    I posted a question on another post related to Ovasitol and I thought of another question.
    Is there a possibility this supplement can cause weight gain? You describe the mechanism and enhancing insulin sensitivity…that would increase the amount of glucose that can enter cells. As seen with insulin injections in those with DM, can this promote weight gain?

    Thank you

  • Angela Grassi

    November 5, 2018 at 1:51 pm

    Ovasitol is not associated with weight gain.

  • Elizabeth

    January 22, 2019 at 12:56 pm

    Is Ovasitol recommended for women with high levels of DHEA-S? I got my bloodwork done and I don’t have high ovarian testosterone. My PCOS is stemming from my adrenals.

  • Angela Grassi

    January 23, 2019 at 5:09 pm

    Yes, it can reduce high levels of DHEA-S

  • Mallory

    January 25, 2019 at 6:08 pm

    Hi, does Ovasitol have the same benefits for women who aren’t diagnosed with PCOS ?

  • Angela Grassi

    February 6, 2019 at 8:48 am

    The research isn’t clear yet. There is emerging research that inositol, the component in Ovasitol can help those with diabetes:http://www.pcosnutrition.com/can-inositol-benefit-type-2-diabetes/

  • Amy

    February 6, 2019 at 7:21 am

    I have only been taking Ovasitol for a week now but I forgot to take a dose before leaving for work this morning. Can I take a double dose in the evening to still get my 2 scoops/day?


  • Angela Grassi

    February 6, 2019 at 8:45 am

    Could you take it at lunch? Research shows it’s best to spread Ovasitol throughout the day instead of 2 at the same time.

  • Lilia

    February 18, 2019 at 2:32 am

    Can it help with hair on the head to grow back / stop the shedding due high testosterone & insulin resistant ??

  • Angela Grassi

    February 22, 2019 at 9:15 pm

    Yes! Ovasitol works to restore hormone balance by lowering insulin and testosterone. Most people find it can help with these symptoms.

  • Nancy J Ekes

    March 12, 2019 at 1:53 pm

    Is Ovasitol processed through your kidneys or have any adverse effects on kidneys?

  • Angela Grassi

    March 25, 2019 at 12:42 pm

    No, ovasitol does not affect the kidneys

  • Iva

    May 31, 2019 at 5:00 pm

    Husband and I have been ttc for over a year with no success. After I came off the pill in April of 2018 my periods became funky and irregular. I skipped several periods and my Dr would put me on Provera to get my period. I am now on my 3rd round of clomid on a higher dose (1000 mg). I didn’t ovulate last cycle and progesterone levels were low. Getting an ultrasound on day 12 of this cycle to check my follicles. Would Ovasitol help me at all???? I also have endometriosis. Thanks in advance for your answer!

  • Angela Grassi

    June 2, 2019 at 4:04 pm

    Yes, definitely! Ovasitol helps improve egg quality and restore hormone balance. The majority of women who take it see a regular menstrual cycle within 3 months.

  • Shivani

    July 6, 2019 at 10:43 am

    Even if I don’t have PCOD, can I take ovasitol as I’m planning for pregnancy.

  • Angela Grassi

    July 7, 2019 at 3:33 pm


  • Donna

    July 16, 2019 at 2:50 pm

    Will this help with estrogen dominance?

  • Angela Grassi

    July 29, 2019 at 10:48 am

    It may help lower estrogen. Ovasitol works to restore hormone balance.

  • Lauren Taylor

    July 17, 2019 at 5:23 pm

    Hi! I’ve been taking this for about a month now and starting my first round of IVF and beginning my stimulation medication today. Should I continue to take this supplement through out my treatment? I know the timing of ovulation has to be precise from my doctor so not sure if I should continue

  • Angela Grassi

    July 29, 2019 at 10:47 am

    yes, ovasitol can be continued during ART

  • Fran

    July 29, 2019 at 9:22 am

    Hi! My daughter is 13 and recently diagnosed with PCOS with elevated insulin levels. May I ask how a child her age should be dosed with the product? We see an endocrinologist next week and I would much rather she try Ovasitol first before oral contraceptives or metformin. Thank you in advance for your guidance!

  • Angela Grassi

    July 29, 2019 at 10:46 am

    Ovasitol has been used in children as young as 8, Yes, it is a great alternative to medication first!

  • Lauren

    August 14, 2019 at 6:55 pm

    Are there any risks if you consume alcohol while also taking ovasitol? Asking for a friend…

  • Angela Grassi

    September 6, 2019 at 10:08 am

    you can consume alcohol while taking Ovasitol but don’t mix ovasitol in alcohol…

  • Anne

    September 5, 2019 at 10:53 pm

    Could someone please advise if this is okay to take with birth control (currently on Yaz)?

  • Angela Grassi

    September 6, 2019 at 9:59 am

    Yes it is!

  • KikiTheWitch

    September 11, 2019 at 11:55 am

    Hi, I am interested in your product, and I would like to know if you have a source for the claim that ovasitol reduces DHEAS levels? Thanks

  • Angela Grassi

    September 11, 2019 at 2:40 pm

    Yes there are several studies that show that myo and d-chiro inositol the ingredients in Ovasitol help to decrease DHEAS levels. Here are a few to check ou:



  • Joy

    September 19, 2019 at 7:51 pm

    I can I double the dosage at night if I forget to take it in the morning?

  • Angela Grassi

    October 3, 2019 at 6:08 pm

    no, ovasitol works best if you spread it out between 2 doses.

  • Nina

    September 24, 2019 at 5:33 am

    Hello ,

    I do not have PCOS but I do have insulin resistance.
    Can I benefit from taking mayo inositol or is this just recommended for women with PCOS?

  • Angela Grassi

    October 3, 2019 at 6:08 pm

    Myo inositol can benefit people who don’t have PCOS. It depends what you want to take it for. For example, it has been shown to lower glucose and insulin, improve fertility and help with anxiety in non-pcos patients.

  • Geeta

    September 25, 2019 at 9:09 am

    Does ovasitol cause hypoglycemia? I took the first scoop today after lunch and after 3-4 hours I started feeling dizzy,feeling of lightheadedness and gastritis.Are these effects due to ovasitol.? Please help.

  • Angela Grassi

    October 3, 2019 at 6:06 pm

    Ovasitol may lower blood glucose level. For that reason, we recommend having it with a meal. We also recommend balanced meals with carbs, protein, and fats to balance blood sugar levels best. I recommend starting with just one dose per day for the first week to make sure you tolerate it ok.

  • Nina

    October 4, 2019 at 9:17 pm

    Hi, how long does it take for ovasitol to start working in your body and notice a change;.?

  • Angela Grassi

    October 8, 2019 at 12:28 pm

    Nina, everyone is different but most of my clients see a reduction in cravings within the first 2 weeks. We do recommend giving it the full 3 months to see a benefit in regulating your cycles.

  • Happiness

    October 10, 2019 at 12:38 pm

    Can ovasitol bring back my menstruation

  • Angela Grassi

    October 31, 2019 at 2:21 pm

    definitely. 90% of women with PCOS see resumption in menstrual regularity within 3 months.

  • Monica Rivera

    November 4, 2019 at 9:25 am


    Can I take Ovasitol combined with Metformin and Birth Control – LO LOESTRIN FE 1-10 TABLET?

    Many thanks

  • Angela Grassi

    November 4, 2019 at 11:48 am

    yes you can!

  • P

    November 19, 2019 at 4:23 am

    The canister says one scoop twice a day. How much is a scoop exactly? Do you mean one heaped table spoon ?

  • Angela Grassi

    November 19, 2019 at 9:23 am

    1 scoop = 1 level teaspoon

  • Kharina

    December 11, 2019 at 10:24 pm

    I have pcos and I want to get pregnant my cycle is every 26 days and I start to tae ovasitol on my second day of my period and the second day of taking it my period had stop is ovasitol causes this side effect ????

  • Angela Grassi

    December 12, 2019 at 10:12 am

    if it’s only been a short time of taking Ovasitol, I doubt that it is from it. We recommend giving ovasitol a good 3 months to help regulate your cycle and improve fertility.

  • Ash

    February 15, 2020 at 10:41 am

    I am considering taking ovositol to help with insulin resistance. I also take birth control in order to prevent pregnancy. Would Ovasitol inhibit the effectiveness of my birth control on preventing pregnancy?

  • Angela Grassi

    February 20, 2020 at 12:50 pm

    no, ovasitol will not affect the actions of your birth control.

  • Theresa Nicole Perez

    February 29, 2020 at 1:07 pm

    My ovasitol expires this month. Will it still work? I have a 90 day supply:/

  • Angela Grassi

    February 29, 2020 at 2:15 pm

    yes, it’s fine!

  • Alicia

    February 29, 2020 at 11:11 pm

    Is it safe take insulin and high blood pressure medicine

  • Angela Grassi

    March 4, 2020 at 9:09 am


  • Jesus

    March 4, 2020 at 8:19 am

    Hi my wife is taking Ovasitol since January 2020. She had her period last February but she is still complaining of breast tenderness and uterine pain even her period ended already 10 days ago. Is it a normal side effects of Ovasitol? Does her hormone still adjusting that is why she still experiencing discomfort? Do you recommend to lessen the dose of her ovasitol then observe for 1 week if the pain still exists? Thank you for your answer admin.

  • Angela Grassi

    March 4, 2020 at 9:09 am

    Hello, Ovasitol should not cause these symptoms. The symptoms you are describing could indicate pregnancy. If she is not pregnant, and symptoms continue, she could cut back to once a day and see how that is for her.

  • Laura F

    March 14, 2020 at 8:08 pm

    I drank some wine but also im taking Ovasitol , Does drinking alcohol affect Ovasitol? Worried

  • Angela Grassi

    March 23, 2020 at 10:59 am

    Moderate alcohol consumption is fine while taking Ovasitol. We do not recommend mixing Ovasitol into your wine or other alcoholic drinks.

  • Mandy Mohr

    March 23, 2020 at 10:37 am

    I am in my 40’s and not looking to get pregnant. I currently have an IUD. Can I take Ovasitol while I still have the IUD? I’m looking to regulate or reduce my symptoms of POCS.

  • Angela Grassi

    March 23, 2020 at 10:57 am

    Yes, Ovasitol can still help to improve metabolic aspects of PCOS. Many people find it also helps to reduce cravings.

  • Tae

    March 23, 2020 at 10:40 am

    I was diagnosed with PCOS in 2017 & my doctor put me on birth control ever since. I just ordered a 3 month supply of Ovasitol & I’m currently confused by what I should do with getting off of the pills. Should I finish a pack then start the ovasitol or should I start taking the Ovasitol immediately then stop once I finish the pack of birth control pills? Help please

  • Angela Grassi

    March 23, 2020 at 10:57 am

    Hello, there is not a need to stop birth control pills while on Ovasitol unless you want to. Otherwise, it’s fine to start taking Ovasitol at any time.

  • Tae

    March 23, 2020 at 3:07 pm

    Thanks so much for the response!!! I want to stop taking the pills so I can start TTC. & start the Ovasitol.

  • Jocelyn

    March 23, 2020 at 9:04 pm

    I had a miscarriage last week. How long should I wait to start taking this. Can I take it right away?

  • Angela Grassi

    March 26, 2020 at 9:42 am

    I am so sorry for your loss. Yes, you can take Ovasitol right away but do check with your doctor.

  • Jyothi

    April 2, 2020 at 5:54 pm

    How long can I use this suppliment. Is there a time limit? I currently use metformin and would like to switch to Ovasitol.

  • Angela Grassi

    April 3, 2020 at 10:29 am

    There isn’t a set amount of time. A lot of people use it for years because they see their symptoms return after a few weeks of stopping it. You can start it while taking Metformin. The two can be taken together. Read this article for more info: https://www.pcosnutrition.com/ovasitol-review/

  • Sara

    April 7, 2020 at 6:36 am

    What would happen if I skip a few days taking the ovasitol because I didn’t order them on time.

  • Angela Grassi

    April 7, 2020 at 9:15 am

    A few days probably won’t make that big of difference but consistency is key.

  • Michelle

    April 16, 2020 at 11:20 pm

    Hi! Thank you for sharing this! Do studies show a difference with the affect of Ovistal and lean PCOS versus standard PCOS and ovaluation? Thank you!

  • Angela Grassi

    April 24, 2020 at 11:04 am

    Thanks! No, we do not know yet if lean women with PCOS respond differently to Ovasitol.

  • MJ

    April 23, 2020 at 1:18 pm

    Hi there – Can you take Ovasitol if you have not been diagnosed with PCOS but have not ovulated in a year (and suspect you have PCOS). Are there any negative side effects to women who may have normal hormonal levels? Thanks in advance!

  • Angela Grassi

    April 24, 2020 at 11:03 am

    Yes you can take Ovasitol if you don’t have PCOS. While research is limited, it may help to improve fertility and ovulation in non-PCOS patients. It is well tolerated and should not have a negative impact on hormone levels.

  • Jessi

    May 15, 2020 at 3:14 pm

    Do I need to be tested for PCOS before using this product? Could it be harmful if I do not have PCOS?

  • Angela Grassi

    May 22, 2020 at 3:25 pm

    No, ovasitol is not harmful. It’s a b-vitamin like supplement. People who don’t have PCOS can take it.

  • Bonnie Moskowitz

    May 19, 2020 at 11:24 pm

    Does Ovasitol increase testosterone if I have have naturally elevated dhea levels?

  • Angela Grassi

    May 22, 2020 at 3:24 pm

    Ovasitol has been shown to decrease testosterone.

  • Aurora

    June 3, 2020 at 11:11 pm

    If you have a regular period before taking the supplement, will it effect it? I have PCOS, but I still get a regular period. I have other symptoms that seem to be helped by Oavsitol, but I don’t want my period to change.

    Thank you,
    Aurora Monteith

  • Angela Grassi

    June 5, 2020 at 2:46 pm

    no, ovasitol should not make your period worse.

  • Melanie Medellin

    June 7, 2020 at 9:27 am

    does anyone know if you can take 2 scoops at once or do i have to divide it into 2 separate times

  • Angela Grassi

    June 8, 2020 at 10:28 am

    Ovasitol is best taken in 2 divided doses.

  • Rafia

    June 8, 2020 at 3:35 pm

    Can I take ovasitol during periods??

  • Angela Grassi

    June 30, 2020 at 1:40 pm

    yes you can.

  • lilia zokaie

    June 30, 2020 at 1:43 pm

    Do I have to take this for rest of my life ?? And will it mess up my menstrual cycle before it fixes it ??

  • Angela Grassi

    August 7, 2020 at 2:56 pm

    Ovasitol can help improve menstrual regularity. As long as it works for you, you can continue taking it.

  • EJ

    July 11, 2020 at 12:36 am

    I took ovasitol with a carbonated beverage. Can you explain why it’s not recommended?

  • Angela Grassi

    August 7, 2020 at 2:54 pm

    Only because it can fizz like a science experiment!

  • Hailey

    August 11, 2020 at 7:16 pm

    Hi I am currently taking birth control and don’t plan on stopping because I don’t want to get pregnant but I have been trying to lose weight and have bad insulin resistance and I have heard good things about this so I was just curious as to if I could take ovasitol and my birth control at the same time?

  • Angela Grassi

    September 3, 2020 at 10:51 am

    yes, you can take Ovasitol and birth control at the same time.

  • susan

    August 13, 2020 at 3:54 am

    My period is regular and am 45 years Can ovasitol help me to conceive…

  • Angela Grassi

    September 3, 2020 at 10:51 am

    Yes it can!

  • Dee Cankaya

    August 27, 2020 at 6:26 pm


    I have started taking Ovasitol today.
    I am very excited to see the positive results!
    But I do have a question – apart from pcos I suffer from anxiety, high blood pressure and migraines.
    Would Ovasitol help with any of these?
    Also, is it ok to take Ovasitol with:
    1. Metformin
    2. Amitriptyline
    3. High blood pressure meds
    4. Sertraline

    Thank you very much in advance.



  • Angela Grassi

    September 3, 2020 at 10:50 am

    Yes, you can take ovasitol with those medications but they all have the potential to lower blood glucose so I would talk with your doctor first. Yes, Ovasitol has been shown in studies to help with anxiety, blood pressure, and migraines.

  • Jay

    August 30, 2020 at 9:01 pm

    Hello! I’m breastfeeding. Can I take ovasitol? Issue is I’ve spoke to two different doctors, and both are pushing me towards birth control instead for PCOS even though I’ve said no many times. They don’t like the idea of me going “rogue” and trying something off the Internet. I’ve taken ovasitol before though which they didn’t like either. So, can I take it? Thank you!!!

  • Jay

    August 30, 2020 at 9:06 pm

    Hello! I’m currently breastfeeding and I wanted to know if I can take ovasitol. I’ve spoke to doctors about it and they said no and instead started pushing me towards metformin and birth control for pcos and insulin resistance. I said no to both many times. I’ve taken ovasitol before and it helped a lot. Can you help me out? Thank you.

  • Angela Grassi

    September 3, 2020 at 10:47 am

    Ovasitol has been shown to be safe for breastfeeding mothers. Since you are not our patient, we can’t advise it though and recommend you talk with your doctor and maybe show the evidence.

  • Jeanette Martinez

    September 1, 2020 at 11:53 pm

    Can ovasital suppress your appetite? I’m currently taking this and I feel like I’m not as hungry or I lose my appetite……. or maybe it’s just me. Also does taking ovasital have any affect on the liver?

  • Angela Grassi

    September 3, 2020 at 10:46 am

    Yes, ovasitol can reduce your appetite because it can lower insulin levels (insulin is an appetite stimulant). No, it should not affect your liver.

  • Dari

    September 5, 2020 at 1:08 pm


    Does Ovasitol help with endometriosis as well?


  • Angela Grassi

    September 28, 2020 at 1:45 pm

    Ovasitol has not been studied well in endometriosis.

  • Alicia perez

    September 17, 2020 at 12:32 am

    I take pen insulin needles is safe take with it or no I take high pressure medicine too are those safe with it because I am trying get pregnant it is safe

  • Angela Grassi

    September 28, 2020 at 1:44 pm

    Yes, you can take Ovasitol with these medications but we recommend checking with your doctor first.

  • Raka

    September 21, 2020 at 9:25 pm

    I am doing OMAD (one meal a day with 23 hours of fasting period) diet. I have PCOS for 2 years..I am going to start Ovasitol for the 1st time. I want to know if it would be alright to have ovasitol while fasting?

  • Angela Grassi

    September 28, 2020 at 1:43 pm

    Ovasitol has not been studied on fasting individuals. We recommend taking Ovasitol with food.

  • Carly

    September 23, 2020 at 1:03 am

    Thank you!! This product helped me conceive my second child after my PCOS diagnosis. My first child was via Clomid and I wanted to try to balance my hormones naturally before going that route again.

    I recently moved house and found some sachets I didn’t realise I hadn’t finished. They expired in Feb of this year, is it too late to take these or can I finish these off before starting my next pack? I have about 2 weeks worth.

  • Angela Grassi

    September 28, 2020 at 1:42 pm

    We recommend not using expired packets from February. So glad to hear Ovasitol helped you conceive!

  • Kelly

    September 24, 2020 at 11:35 pm

    I have PCOS WITHOUT insulin resistance and my cholesterol levels are low. Can Ovasitol cause either of those to go even lower in someone with already low levels?

  • Angela Grassi

    September 28, 2020 at 1:41 pm

    Ovasitol does have the potential to lower glucose and insulin. Everyone is different. Some people find taking one dose a day is sufficient to help regulate periods.

  • Raka

    September 25, 2020 at 7:41 pm

    Can I take ovasitol in 7 days water fasting?

  • Angela Grassi

    September 28, 2020 at 1:40 pm

    We do not recommend fasting that long and cannot comment about taking Ovasitol during that time.

  • Cam

    October 7, 2020 at 3:03 pm

    Thank you for your helpful website and info on Ovasitol. I’ve started and stopped this several times because of side effects. Each time I start it off, it seems to cause nausea/fatigue for me so I stop. Is this normal? I do take it with meals and have only started 1x day for the first week. But after several days I start to get these symptoms. Are these symptoms normal and will they eventually subside?

  • Angela Grassi

    November 3, 2020 at 9:48 am

    Ovasitol is a sugar alcohol. Maybe try and stick to one dose for a month, with food to see if side effects improve.

  • Camille

    October 16, 2020 at 1:39 pm

    I’m having side effects of nausea and fatigue after a week of using Ovasitol. Will it go away and is this a common side effect?

  • Angela Grassi

    November 3, 2020 at 9:46 am

    You may want to start slower, with just one dose a day with a meal and after a week, add a second dose.

  • Stef

    November 16, 2020 at 6:39 am

    I have suffered with pcos and endometriosis for 30 years and have finally had a hysterectomy… have been taking ovasitol for a year now and wondered has ovasitol been used sucessfully to help menopausal symptoms…

    Really look forward to a reply

  • Angela Grassi

    November 16, 2020 at 4:42 pm

    Yes, many of my patients who have had a hysterectomy have found Ovasitol helpful. here’s some more info about it: https://www.pcosnutrition.com/pcos-and-hysterectomy-is-it-a-cure/

  • daelle glidden

    November 20, 2020 at 10:49 pm

    Is it possible to take to much? I’m very new to this and wondering how this will affect my Insulin levels. My doctor gave me 2 options one was birth control the other he said was a pill used for Diabetes witch he told me he checked me for diabetes and I didn’t have them. So he said I could pick what one I wanted to take but he would recommend me not messing with my diabetes numbers. Could taking this be harmful?

  • Angela Grassi

    December 31, 2020 at 10:28 am

    Ovasitol can be taken with birth control and diabetes medications.

  • Jen

    November 24, 2020 at 5:54 pm

    So i have PCOS im currently on spironolact 50mg & metformin 500mg as well birthcontrol Xulane (150/35 mcg) so i just got this product bc i dont want be taking so many meds … i told my doc he said okay dont take nothing and try it see how it works for me but not sure if the birthcontrol is okay to still be on it? Because is for (noreglgestromin and ethinyl estradiol transdermal system) i have high tolerance insulin , super high Testosterone levels and consider overweight…. any recommendations? Still okay to take 2 a day?

  • Angela Grassi

    December 31, 2020 at 10:26 am

    Yes, ovasitol does not interfere with birth control

  • Nyilla bah

    December 1, 2020 at 11:01 am

    how long should a woman take ovasitol

  • Angela Grassi

    December 31, 2020 at 10:24 am

    No set timeline

  • Monique

    December 7, 2020 at 12:17 am

    Will taking ovasitol or even inositol alone reduce effectiveness of birth control? As I know birth control is not 100% , does it increase chances of getting pregnant while taking birth control?

  • Angela Grassi

    December 31, 2020 at 10:23 am

    No, Ovasitol does not interfere with birth control

  • Smartinez

    December 9, 2020 at 1:51 pm

    I was on BC (implanon) for SEVEN years! I finally removed it this year in January- I had no period for 4 months after removing BC. I was diagnosed with PCOS in June.
    Obgyn prescribed progesterone, started this in July and had a period. November came along and I lost excess amount of hair, my hair continues to fall out. I decided to not take anymore medication. Here we are in December and hair is still falling out.
    Do you know of any other women experiencing this? I have ordered Ovasitol and hope it helps. I am desperate to know since I want to salvage as much hair.

  • Angela Grassi

    December 31, 2020 at 10:23 am

    Most birth control medications suppress testosterone. It is not unusual to see symptoms worsen if stopping birth control. I hope ovasitol works for you. Here are more tips on hair loss: https://www.pcosnutrition.com/hair-loss/

  • Zoya

    December 26, 2020 at 2:21 pm

    I have not had my regular periods from past 1 year and was on progesterone medication to regular my cycle. I have ordered my first supply of ovasitol and wanted to check if I can take it along with my medicine. My doctor hasn’t heard about ovasitol.

  • Zoya

    December 27, 2020 at 1:31 pm

    Can I take Ovasitol with progesterone medicine my doctor has given?

  • Angela Grassi

    December 31, 2020 at 10:20 am

    yes but we recommend discussing with your doctor first.

  • NM

    December 30, 2020 at 2:17 pm


    I have been experiencing heavy bleeding (rare form of PCOS). I am currently taking norothesterone for 21 days and then taking a weeks break.

    Is it safe to take ovasitol at the same time as norothesterone?

  • Angela Grassi

    December 31, 2020 at 10:15 am

    Yes, ovasitol can be taken if you are also taking birth control medications.

  • Jennifer Agnew

    December 31, 2020 at 9:47 am

    Has anyone ever stopped taking ovasitol and still got cramping every day and other symptoms like nausea, aches and pain, headaches. I’ve been trying to figure out if I’m pregnant as I only took ovasitol for 2.5 months and the cramping is daily still. I don’t see any reviews or withdrawals . Please help.

  • Steph

    January 3, 2021 at 1:24 pm

    If my canister expiration date is 9/20, should I order a new one or is it still good? I have at least half a canister left but I want to be sure before taking any. Thanks!

  • Angela Grassi

    January 15, 2021 at 2:06 pm

    Probably best to reorder

  • Steph

    January 3, 2021 at 8:02 pm

    Can you take Ovasitol past the expiration date?

  • Angela Grassi

    January 15, 2021 at 2:05 pm

    yes, but just a few months out

  • Vanessa

    January 13, 2021 at 9:56 pm

    I’ve been taking ovasitol for about a week now and have noticed cramping like before my periods starts kind of crampings. Is this normal from taking ovasitol? It’s the only new thing I have added to my supplement routine. Also Ive been on metformin for about 6 months and never had cramping as a side effect.

  • Angela Grassi

    January 15, 2021 at 2:04 pm

    Yes, this is not uncommon. What you described sounds like signs of ovulation.

  • Satvika

    January 16, 2021 at 3:22 pm

    Will there be a spike or any adverse effect if I stop consuming ovasitol in the future ? Like since my body will be used to this supplement to lower my insulin levels will stopping this cause any spike in the the insulin levels and will it in turn cause weight gain and have other effects

  • Angela Grassi

    February 14, 2021 at 8:01 pm

    Good question! The long-term research on this supplement after taking is still unknown. Keep in mind, inositol is widely found in food and a relative of the b-vitamins.

  • Nicole

    January 23, 2021 at 12:59 am

    Is it safe to take Ovasitol after having blood clots?

  • Angela Grassi

    February 14, 2021 at 8:00 pm

    Yes, Ovasitol can safely be taken if you had blood clots but we always recommend consulting with your doctor before use.

  • Brittney

    January 28, 2021 at 11:29 am

    Is ovasitol beneficial for women who have had a hysterectomy?

  • Angela Grassi

    February 14, 2021 at 7:59 pm

    Yes it is! Ovasitol can help with many of the metabolic aspects of PCOS.

  • Maria

    February 2, 2021 at 2:46 pm

    if I am on birth control pill to control pcos symptoms can I take this supplement and continue the birth control pill. I am trying to improve insuline resistance.

  • Angela Grassi

    February 14, 2021 at 7:59 pm

    Yes, you can take Ovasitol while on birth control pills.

  • Noemi

    February 3, 2021 at 5:21 pm

    I started taking it 3 days ago and my my acne is starting to flair up. Is this normal? Is it because my hormones are balancing or do you recommend me to stop drinking it? Thanks!

  • Angela Grassi

    February 14, 2021 at 7:58 pm

    No, Ovasitol should help improve acne, not worsen it. I highly doubt it would affect you after 3 days of use.

  • Megha Desai

    February 14, 2021 at 7:29 am

    I came off the pill last year and haven’t had a period. I have done a lot of research which says d-chiro inositol can be bad for egg quality on its on own. I have in the past only taken myo-inositol but discovered this combined inositol.

    Can you confirm if this helps with ovulation and can be used for fertility and doesn’t effect the egg quality?

  • Angela Grassi

    February 14, 2021 at 7:58 pm

    Yes, Ovasitol has been shown to help improve ovulation and is great for helping to get pregnant. Very high doses of d-chiro inositol (over 600mg daily) has been linked with poor fertility. Ovasitol uses a ratio of myo to DCI in a 40:1 ratio to mimic levels in the body.

  • Esther v

    February 20, 2021 at 8:55 pm

    I’ve looked so many times to see how long is it safe to take ovasitol.
    I see studies only go with 6 months of taking ovasitol. Outside of that, is it ok to keep taking it and if so for how long?
    Thank you!

  • Angela Grassi

    March 25, 2021 at 12:51 pm

    We really don’t know. As long as it works for you, you can continue to take Ovasitol long-term.

  • Krystal Martinez

    March 9, 2021 at 10:49 pm

    I do not have PCOS but I have irregular periods, I sometimes go up to 9 months without it. I do not have Insulin issues either. But I’ve read this helps women get pregnant. Is this safe for me to take even though I don’t have PCOS or insulin issues? I’m just trying to get regular and try to have a baby.

  • Angela Grassi

    March 25, 2021 at 12:48 pm

    Oasitol helps 90% of my patients get their periods back. It has been shown to help with ovulation and improving egg quality.

  • Megan

    March 12, 2021 at 12:12 pm

    Why can it not be mixed in with carbonated beverages?

  • Angela Grassi

    March 25, 2021 at 12:47 pm

    It will cause fizziness.

  • Sally Beth Campusano Santos

    March 13, 2021 at 3:07 pm

    My period came a week after starting ovasitol. It lasted 9 days.

    After the main bleeding ended I kept spotting and it’s been 4 days of just spotting and all of a sudden I am bleeding again with all my PMS symptoms.

    Is that normal? Should I stop taking ovasitol while on my period?

  • Angela Grassi

    March 25, 2021 at 12:46 pm

    No, this is not a normal response to taking Ovasitol. I suggest contacting your doctor to see what else may be causing the prolonged and frequent bleeding.

  • Stephanie Rodriguez

    March 13, 2021 at 4:20 pm

    Hi, I was diagnosed with disordered proliferative endometrium. Will this help?

  • Angela Grassi

    March 25, 2021 at 12:45 pm

    I don’t believe inositol has been studied with your condition.

  • Gabrielle

    March 17, 2021 at 7:16 pm

    Can you take this while on birth controls? Specifically Gianvi? My doctor has no clue what PCOS even is and just prescribed a birth control.

  • Angela Grassi

    March 25, 2021 at 12:45 pm

    Yes, Ovasitol can be taken while on oral contraceptives.

  • Prabh

    March 28, 2021 at 3:59 pm

    Can non pcos or pcod women consume it too ?

  • Angela Grassi

    April 9, 2021 at 3:55 pm


  • Sarah

    March 30, 2021 at 2:52 am

    Is it okay if I take Ovasitol with these supplements?
    1. PCOS Nutrition Center N-ACETYL CYSTEINE (NAC)
    3. PCOS Nutrition Center Berberine Plus

  • Kim smith

    March 30, 2021 at 10:02 am

    If you start taking ovasitol do have you have to continuously use the product

  • Angela Grassi

    April 9, 2021 at 3:54 pm

    A minimum of 3 months of continuous use is recommended for best results. It can be taken longer if working well.

  • Sarah

    March 30, 2021 at 3:01 pm

    Hello, I’m wondering if I can take Ovasitol with these supplements:
    1. PCOS Nutrition Center N-ACETYL CYSTEINE (NAC)
    3. PCOS Nutrition Center Berberine Plus

  • Angela Grassi

    April 9, 2021 at 3:54 pm

    Yes, all of our supplements can be taken together but we always recommend checking with your doctor.

  • Ariel

    April 8, 2021 at 5:40 pm

    Is Ovasitol ok to take for TTC if I don’t have PCOS, irregular cycles, or insulin resistance?

  • Angela Grassi

    April 9, 2021 at 3:52 pm

    Yes, ovasitol still can help to improve egg quality and ovulation.

  • Amy

    April 9, 2021 at 3:37 pm

    I’m interested in trying this product for my PCOS. I take a women’s multi vitamin that I really like that has 600mg of Mayo-Inositol. Can I still take this with that?

  • Angela Grassi

    April 9, 2021 at 3:51 pm

    Yes, depending on how much inositol it has.

  • Britney

    April 11, 2021 at 8:34 am

    I’ve been taking Ovasitol for 2 months now, really do believe in the product, haven’t had any improvements in regards to a regular period but I do think that’ll come with more time. My question is, can I continue to take with either clomid or letrozol? (Drugs to help you ovulate/fall pregnant).
    Thank you

  • Angela Grassi

    April 28, 2021 at 5:05 pm

    It is recommended to take ovasitol for the full 3 months for best benefits. Yes, you can take while undergoing clomid or letrozole. Talk to your doctor first though.

  • Brit

    April 11, 2021 at 9:30 am

    Can I take Ovasitol the same time as taking letrozol or clomid?

  • Angela Grassi

    April 28, 2021 at 5:05 pm

    yes, but of course, talk with your doctor about it.

  • Faiza Naeem

    April 12, 2021 at 3:25 pm

    Can I take this supplement during periods??
    As like we have to stop taking birth control during periods. So is it the same case ?
    Or I can take it during my periods too?

  • Angela Grassi

    April 28, 2021 at 5:04 pm

    It is recommened to take Ovasitol consistently. No breaks are needed.

  • Mary

    April 14, 2021 at 1:08 pm

    I’m having the same symptoms as Sally Beth Campusano Santos, except my period started about 2 weeks after and is not stopping like it normally would. Did you keep taking it Sally Beth Campusano Santos?

  • Beth Adams

    April 19, 2021 at 2:55 pm

    Does this help women with a hysterectomy, but still have their ovaries? And yes, have PCOS.

  • Angela Grassi

    April 28, 2021 at 5:03 pm

    Yes, you can take it if you still have ovaries. Here is an article you may find helpful: https://www.pcosnutrition.com/pcos-and-hysterectomy-is-it-a-cure/

  • Adina Koch

    May 2, 2021 at 9:12 pm


    Is it ok to mix ovasitol and powder fiber supplement into the same beverage?

    Thank you,

  • Angela Grassi

    May 4, 2021 at 10:00 am

    yes, that is fine.

  • Kristie Chavis

    May 15, 2021 at 10:15 am

    Does it expire ?

  • Angela Grassi

    June 12, 2021 at 2:54 pm

    Yes, Ovasitol has an expiration date on each package.

  • Karen

    May 15, 2021 at 11:17 pm

    Can ovasitol be taken with an antidepressant? I take Lexapro would it interact?

  • Angela Grassi

    June 12, 2021 at 2:54 pm

    Ovasitol can be taken with lexapro but we do recommend consulting with your doctor. Ovasitol has been shown to help with mood.

  • Haley

    May 19, 2021 at 10:15 am

    I wanted to comment too, because I asked the Theralogix support team, Ovasitol CAN be mixed into carbonated beverages, but just be careful because it can cause it to bubble and spill (think mentos and diet coke but way way way way way less). As long as it isn’t a full glass and you leave some room, it is fine. They said it doesn’t change the way the supplement works or anything, they just caution it for the potential mess.

    Also, (of course consult your doctor as was stated above!) but just for anyone curious about the Ovasitol and Metformin together, I was taking Ovasitol long before I started the Metformin and for me they are totally fine together. The only time I noticed my stomach feeling a little off with the Ovasitol was when I accidentally took 2 doses one morning. Some people take their 2 doses together (some other Inositols also just have a higher dosage 1x/day) and have no problem with that too so it very much varies person-to-person like most supplements.

    Example: I tried a Berberine, and it gave me horrible heart palpitations, it took me a week to realize that’s what it was, and then I tried a Magnesium/Calc/Zinc and it made me sick, like vertigo and weirdness very unpleasant–**neither of these were from this site**, but so many people have really good experiences with those supplements as alternatives to Metformin because of the potential for side effects (which I’ve been so very fortunate to actually respond really well to and not have much of any side effects), so it just goes to show how different people can be when it comes to this stuff.

  • Leticia Chico

    May 22, 2021 at 8:59 pm

    I do not have pcos. I have type 2 diabetes and take 1000 mg of metformin, 4 mg of glimepiride, 100 mg of Januvia, 65 mg of iron. Am I able to take Ovasitol?

  • Angela Grassi

    June 12, 2021 at 2:52 pm

    Ovasitol can be taken safely with these medications as it is a b-vitamin like compound but we do recommend consulting with your doctor first.

  • Jean

    May 31, 2021 at 4:02 pm

    Can I start ovasitol during my two week wait? Or should I wait for my next cycle to start if this one isn’t successful

  • Angela Grassi

    June 12, 2021 at 2:50 pm

    Ovasitol can be taken any time of the month but we do recommend talking with your doctor first if undergoing fertility treatments.

  • Susanne

    June 2, 2021 at 6:50 pm

    I don’t want to get pregnant and got ovasitol for my hormone Inbalance, mood swings, and PMDD. However I need a birth control still. I read that you can take a lo estrogen birth control with it. Will ovasitol contradict the affects of the birth control and will the birth control still be effective? I want to avoid pregnancy.

  • Angela Grassi

    June 12, 2021 at 2:49 pm

    Ovasitol does not affect birth control medications.

  • Tayyaba Irfan mughal

    June 5, 2021 at 10:09 am

    Can we take ovasitol while being on birth control ? Does it stop the effete of birth control like Desogestrel ? Or it’s okay to take both together ?

  • Angela Grassi

    June 12, 2021 at 2:49 pm

    Ovasitol does not affect birth control medications.

  • Saba

    June 6, 2021 at 7:15 pm

    Hello i am 25 years old after first birth of my child i started abdominal and back pain i had 2 miscarriages and after 4 years of pain i diagnosed with pcos doctors removed cysts from my left ovary but still suffering with abdominal and back pain my muscles are very weak all the time i feel muscles pain and gastric problum i want to know if this product will help me because i read about side effects there is mentioned about muscle pain

  • Angela Grassi

    June 12, 2021 at 2:49 pm

    Ovasitol may help with that.

  • Kmj

    June 7, 2021 at 8:56 pm

    I had a breast reduction a few years ago. Is breast growth a side effect to ovasitol I would need to worry about? I do not want to risk them getting big again, thanks!

  • Angela Grassi

    June 12, 2021 at 2:48 pm

    No, Ovasitol does not affect breast growth

  • Melissa

    June 18, 2021 at 10:44 pm


    Can I take ovasitol even I I don’t have PCOS but just trying to bring my periods closer together and get pregnant?

    Also, can ovasitol cause spotting?

  • Angela Grassi

    July 26, 2021 at 2:17 pm

    Yes, ovasitol can be helpful for regulating periods and shortening cycles. It can cause spotting at first.

  • Amanda Mayes

    June 20, 2021 at 8:57 pm

    I get cyst a lot and weight gain and acne of pcos but I have monthly periods. Would ovasitol still be a good choice for me?

  • Angela Grassi

    July 26, 2021 at 2:17 pm

    Ovsitol can still be taken if you have regular periods. Here are some other supplements to consider: https://www.pcosnutrition.com/product-category/supplements/

  • Alexandra

    July 4, 2021 at 1:04 pm

    Hi, I have been taking ovasitol for about two weeks and am moving towards a keto diet. The combination of the two has left me often not hungry for periods of time, I am looking to incorporate some short term fasting (half/full day), but would like to continue taking ovasitol twice a day.

    I know it is recommended to take ovasitol with food, but is it safe to take on its own as well? Would it be less effective or cause a spike in insulin because it is carb based?

  • Angela Grassi

    July 26, 2021 at 2:15 pm

    Ovasitol will not cause a spike in insulin and should be taken with food.

  • Chrissy

    July 16, 2021 at 5:53 pm

    Can I take ovasitol while having an iud in place? I have the kyleena. Thank you

  • Angela Grassi

    July 26, 2021 at 2:12 pm

    Ovasitol will not affect an IUD

  • Racheal

    July 20, 2021 at 1:34 pm

    Does Ovasitol help with excess hair. I have PCOS and experience a lot of hair on my chest, chin, side burns etc
    Also is it fine to take while on Yasmin?

  • Angela Grassi

    July 26, 2021 at 2:10 pm

    Yes, ovasitol can help to reduce testosterone and hair growth. You may also find this article helpful:https://www.pcosnutrition.com/testosterone/

    Ovasitol can be taken safely with birth control medications.

  • Anam Zafar

    July 23, 2021 at 7:25 am

    Just a quick question
    I’m on my periods now with ovasitol but its really heavy flow and I’m on heavy flow for past 5 days now…its been 7 days and no sign of end of them

    Is it because I’m taking ovasitol during periods?
    Should I quit until my periods end?
    Is it normal to have this much flow and for this long?

  • Angela Grassi

    July 26, 2021 at 2:08 pm

    We recommend using Ovasitol twice a day continuously for 3 months for best results.

  • Alisa

    July 23, 2021 at 11:11 am

    Will I still see results with taking half the dosage of Ovasitol? Thank you.

  • Angela Grassi

    July 26, 2021 at 2:07 pm

    You may. Some people do, especially after finishing the first 3 months. It would be important for you to monitor symptoms and blood results if you cut back to half the dose.


    August 3, 2021 at 11:06 am

    I want to know that can we give ovasitol to a pt with PCOS with a period more than a year?is there any side effects?

  • Yesenia

    August 8, 2021 at 12:08 am

    My period became irregular after I had a mirena IUD removed. My cycle is currently 21 days or less. I am trying to get pregnant. Will ovasitol help me conceive? I do not have PCOS.

  • Angela Grassi

    August 16, 2021 at 7:36 am

    Ovasitol promotes normal mestrual regularity and helps to improve egg quality.

PCOS Nutrition Center

Sign Up!

PCOS Nutrition Center