Should you Take a Multivitamin?

Should you take a multivitamin if you have PCOS? This is one of the popular questions we hear from our patients at the PCOS Nutrition Center. Certainly many with PCOS may be taking other supplements to help manage their PCOS, do they really need a multivitamin on top of those pills? How much is too much? What should you look for in a multivitamin? Here’s what to know about taking a multivitamin if you have PCOS.

Supplements Shouldn’t Replace Food

A pill can’t substitute for the fiber content or the numerous health benefits from the synergy that a variety of whole foods provide.

But the reality is most people don’t eat a diet that includes at least half of whole grain foods or the 9 to 13 servings of fruits and vegetables needed each day. And for the one out of 6 Americans facing food insecurity at some point in their lives, meeting these nutrient requirements through food is next to impossible.

Supplements Prevent Deficiencies

In some cases, it’s clearly beneficial to take a multivitamin to prevent a deficiency or to help maintain adequate levels of nutrients.

Take women who are trying to conceive. Taking a multivitamin or prenatal vitamin helps ensure an adequate amount of necessary nutrients for fetal growth like folic acid or folate, choline, and omega-3 fats, all crucial for fetal brain development.

Vegans need to supplement their diets with vitamin B12.

People who take metformin, birth control pills or heart burn medications should also supplement their daily nutrition with vitamin B12 to prevent a deficiency. Didn’t know about this? Head over to our blog post about the Mandatory Supplementation of Vitamin B12 if you take Metformin.

People with certain types of anemia may require iron supplementation.

Multivitamins can help prevent nutrient deficiencies in those that are malnourished due to poverty or food insecurity, restrictive diets or food allergies or intolerances.

Women with PCOS Have Nutrient Deficiencies

While I do think that most individuals who eat a healthy diet that meets their nutrient requirements, don’t need a multivitamin, I do think individuals with PCOS would benefit from taking one. The reason is because women with PCOS have been shown to be at a higher risk of numerous nutrient deficiencies such as the following:


Magnesium is an important mineral that most people with polycystic ovary syndrome (PCOS) are significantly lacking in. Women with PCOS are 19 times more likely to have a magnesium deficiency, according to a study in Gynecology Endocrinology. This is concerning as magnesium has been shown to play a role in glucose, insulin, and blood pressure regulation. Individuals with metabolic syndrome or type 2 diabetes have also shown to have low levels of magnesium. In fact, having low levels of magnesium increases your risk for having type 2 diabetes.


Zinc levels have also been shown to be lower among the PCOS population. Zinc is an essential trace metal that plays a role in menstrual cycle regulation.

Zinc works to inhibit testosterone from converting to its non-aromatizable form, dihydrotestosterone (DHT), which is how it can reduce hair loss as well as other symptoms associated with high testosterone levels in women with PCOS like acne, hair loss, and unwanted hair growth.

Vitamin D

Low vitamin D status is highly prevalent among the PCOS population. Vitamin D is a vitamin but also a hormone that’s involved in metabolic health. A deficiency of vitamin D contributes to poor egg quality and infertility.

READ 3 Major Roles of Vitamin D for PCOS

Vitamin B12

People with PCOS need to make sure they are getting enough vitamin B12. Why? Metformin, oral contraceptives, and common heartburn medications can deplete levels of vitamin B12. Conditions that interfere with nutrient absorption, such celiac or Crohn’s disease, can also affect levels of B12. Read our popular blog post 7 Signs You’re Not Getting Enough Vitamin B12

pcos supplement quiz

Supplements Don’t Treat Diseases

Dietary supplements aren’t intended to treat diseases. The roles vitamins and minerals are involved in include maintaining normal cell function, metabolism, growth and development, and act as essential cofactors in hundreds of enzyme reactions throughout the body.

Vitamins and minerals may help improve certain aspects of medical conditions such as insulin sensitivity in PCOS, but they won’t cure PCOS or any other disease.

Multivitamins and any other dietary supplement shouldn’t replace food, especially whole foods which can help heal PCOS. But they can improve many aspects of the condition and maintain good health.

Shopping For a Multivitamin

Dietary supplements are not regulated like drugs are. Anyone can put a dietary supplement on the market without prior testing. Pretty crazy when you think about it, huh?

When looking for a multivitamin, look for a pharmaceutical-grade quality one. It may be pricier, but chances are, the product has been manufactured in a FDA compliant facility.

Look to see if the multivitamin has been 3rd party tested. This means an independent lab not associated with the manufacturer has done their own testing to make sure the supplement is meeting requirements on the label and is free from contaminants.

As a reminder, all the supplements in the PCOS Nutrition Center Store have been independently tested by a third party and manufactured in an FDA compliant facility.

PCOS Nutrition Center PCOS MULTI®

Knowing many people with PCOS are not getting enough vitamins and minerals, and how important certain vitamins and minerals are for PCOS, we specifically formulated PCOS MULTI to help meet these needs.

PCOS MULTI® contains extra amounts of B-vitamins, vitamin B12, vitamin D, zinc folate, and other antioxidants to support health in those with PCOS.* All this in just 2 small capsules…because no one needs to be swallowing more pills than bites of breakfast.

The PCOS Nutrition Center PCOS MULTI® is the only multivitamin specifically formulated to meet the unique health needs of people with PCOS.* and is manufactured in an FDA compliant facility and is 3rd party tested by an independent lab.


Need other supplements to help you manage PCOS? Visit our supplements store for a variety of medical-grade supplements that are 3rd party tested and specifically formulated for women with PCOS.



Sharifi F, Mazloomi S, Hajihosseini R, Mazloomzadeh S. Serum magnesium concentrations in polycystic ovary syndrome and its association with insulin resistance. 2 Gynecol Endocrinol. 2012;28(1):7-11.

Siahbazi S. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial. 2017. J Obstet Gynaecol Res.

Jamilian M, Foroozanfard F, Bahmani F, Talaee R, Monavari M, Asemi Z. Effects of Zinc Supplementation on Endocrine Outcomes in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial. Biol Trace Elem Res. 2016 Apr;170(2):271-8.

Baillargeon JP, Iuorno MJ, Apridonidze T, Nestler JE. Uncoupling between insulin and release of a D-chiro-inositol-containing inositolphosphoglycan mediator of insulin action in obese women With polycystic ovary syndrome. Metabol synd related disorders. 2010;8(2):127-136.

Cheang KI, Baillargeon JP, Essah PA, et al. Insulin-stimulated release of D-chiro-inositol-containing inositolphosphoglycan mediator correlates with insulin sensitivity in women with polycystic ovary syndrome. Metabolism. 2008;57(10):1390-1397.

Wehr E, Pilz S, Schweighofer N, et al. Association of hypovitaminosis D with metabolic disturbances in polycystic ovary syndrome. Europ J Endocrinology. 2009;161(4):575-582

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Comments (5)
  • PredatorNutrition

    March 1, 2019 at 8:24 am

    I always thought that supplements are never beneficial until I visited this post and got to know about their importance. Thank you so much for making me realize the significance of supplements.

  • Viah

    March 9, 2019 at 10:58 pm

    Thank you for this post.

    But what are your thoughts about gluthatione for PCOS. Would you say it can be an important supplement for fertility as well?.. Looking forward for your reply. Thank you.

  • Angela Grassi

    March 25, 2019 at 12:44 pm

    Glutathione is important but research is lacking. Here are the supplements for the best evidence in helping with fertility:

  • Sherrill Pring

    April 18, 2019 at 6:43 am

    Hi I am really worried about what will happen to my pcos. I’m 55 yrs old and now the Dr’s and the Endocrinologist won’t give me Diane 35 which is what I’ve been on all my life. This pcos isn’t going to get better. If I come off this pill my whole system is one complete mess. It’s alright for these Dr’s to say you can’t take this & that but it’s my life, my body not theirs.
    Please help me

  • Anna Davis

    May 21, 2021 at 12:26 am

    It’s interesting that vitamins can improve certain aspects of your health. I have been thinking about getting a multivitamin. It seems like a good idea considering my diet doesn’t have a lot of variety.

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